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Its principal molecular activity is G-actin sequestration via the conserved 'LKKTET' actin-binding motif in the N-terminal region

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It is superimposed on the fractions of each Niclosamide species (Nic OH and Nic -ve ) (left axis) from the Henderson Hasselbalch analysis (from Figure S3 )

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It's actually the first pharmaceutical ever prescribed in this country in the late 1800s, was methylene blue

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