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Biomarkers of ROS and clinical translation: from bench to bedside section translates the framework into practice with clinically oriented biomarker panelslayering species-level reporters with damage footprints and iron metricsand provides implementation pathways, validation standards, and disease-anchored examples (e.g., ICU use-cases and oncology/neuro/metabolic panels)

GLP-1RAs reduce the expression of cholesterol synthesis and bile acid synthesisassociated genes by inhibiting SREBP-2 in HepG2 cells treated with PA To investigate whether SREBP-2 inhibition mediated by GLP-1RAs affects the expression of cholesterol metabolism-related genes, HepG2 cells were transfected with SREBP-2 siRNA for 24 hours, followed by PA and GLP-1RA treatments

Those with uncontrolled systemic diseases (e.g., diabetes, malignancy, autoimmune disorders) must achieve stabilization