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Name: is retatrutide more expensive than tirzepatide What vs Tirzepatide? Retatrutide vs Tirzepatide (2026): Differences
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The high cost of GLP-1s is a key factor in this disparity

Dardiotis E, Kyriakides T

Lancet (2021) 398:181124

Gilbert, Rosenthal, Jan 2024)

Zhais team (Zhai et al., 2020) found that exendin-4, a GLP-1 receptor agonist, enhances eNOS activity and NO production, which helps relax retinal capillaries and restore microvascular perfusion in ischemia-reperfusion (I/R) injury models