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Novo Nordisk filed the New Drug Application (NDA) for CagriSema in early 2026, based on positive results from the REDEFINE phase 3 trial program

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Interestingly, BPC-157 peptide for gut health is another area of active research

A few patterns recur often enough to address up front: borderline BMI just under a tier threshold, type 2 diabetes paired with a non-diabetes condition, prediabetes paired with a BMI above the Tier 3 range, and patients who meet more than one tier

Similarly, Gastaldelli et al