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This correlation is believed to be due to widespread autoimmune processes, such as destruction of thyroid follicular cells and epidermal melanocytes by cytotoxic CD8 T cells and increased levels of antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-TG) antibodies in patients with vitiligo

Research found no evidence of tolerance development, receptor desensitization, or accumulating side effects over the study periods

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Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation

Author contributions FW: Conceptualization, Data curation, Writing original draft, Writing review & editing