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Trapp, S., & Brierley, D

Semaglutide is an effective medication with strong clinical data behind it

By reducing hunger and promoting feelings of fullness, GLP-1 injections make it easier to stick to a balanced diet, ultimately leading to a reduction in calorie intake

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That triple agonism is generating intense interest in pre-clinical metabolic-research circles, where investigators are comparing it head-to-head against the dual agonist Tirzepatide and the GLP-1 mono-agonist Semaglutide

Exenatide upregulates gene expression of glucagon-like peptide-1 receptor and nerve growth factor in streptozotocin/nicotinamide-induced diabetic mice