Both drugs belong to a class of groundbreaking weight loss drugs known as GLP-1 receptor agonists, or more simply GLP-1s. GLP-1 agonists work by mimicking glucagon-like peptide-1 (GLP-1), a natural hormone that is involved in regulating blood glucose levels as well as how long food remains in your stomach
Take 2 capsules daily, 30 minutes before a meal or as directed by a health care professional
These ligands bind to TRAIL receptors 1 and 2 (TRAIL-R1/-R2) or the CD95/Fas receptor on target cells, ultimately inducing cell death [172]
Given the existing elevated risk in people with obesity, 7 and taking into account current research gaps, efforts to minimize that risk should be a routine part of current obesity care
GLP-1 medications offer several important benefits for individuals looking to lose weight
For clinicians managing patients with both inflammatory arthritis and obesity or type 2 diabetes mellitus (T2DM), this could certainly change how we think about comorbidity management