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however, the extract did not influence incretin levels [40]

(2023) 120:e2209944120

DSIP indirectly increases nocturnal GH by deepening delta-wave sleep, the phase where the largest daily GH pulse occurs

It works through a different mechanism than GHK-Cu: PDRN activates the A2A adenosine receptor, which triggers tissue regeneration, dampens inflammation, and supports the cellular metabolism of dermal cells