For instance, in carotid endarterectomy procedures for diabetic patients, preoperative administration of GLP-1 RAs has been demonstrated to markedly enhance the expression of proteins that improve inflammatory pathways in diabetic atherosclerotic lesions, thereby promoting plaque stabilization [106]
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#Fisiologa #GLP1 Receptores de GLP-1 Los receptores de GLP-1 se encuentran en diversas partes del cuerpo, incluyendo el pncreas, cerebro , y tracto gastrointestinal
Adipose tissue-derived free fatty acids (FFAs) impair renal urate excretion via URAT1 upregulation, while hyperuricemia reciprocally induces insulin resistance and endothelial dysfunction through AMPK inhibition and oxidative stress (Xu et al., 2015)
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