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Subcellularly only 10% of total TPP is available for binding to transketolase most of it is associated with the mitochondria [185].Thiamine and its acid metabolites are are excreted primarily in the urine [195]

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By being mindful of potential interactions with medications, choosing the right foods, and adhering to recommended dosages, you can maximise the benefits of this powerful antioxidant

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How to take and dosing 2.5g per day is most common dosing, sometimes split into 2 doses but likely not necessary unless GI effects noted