Figure 1 Bioinformatics analysis We primarily utilized Ingenuity Pathway Analysis (IPA) from Ingenuity Systems to perform functional pathway analysis of the differentially expressed proteins (DEPs)
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The DHS-led survival advantage of mice was accompanied by an increase in the total GPx activity as well as mRNA expression levels of seleno-GPxs ( GPx1 , GPx2 , GPx3 , and GPx4 ), reduction of lipid peroxidation, and suppression of inflammatory response (decrease of the expressions of pro-inflammatory genes and infiltration of inflammatory cells) in the radiosensitive organs such as spleen, intestine, and lung
These are generally high doses of IV drips or glutathione , combined with vitamin C and antioxidants
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