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For instance, the gain of function or loss of function mutations of transcriptional co-activators upregulate oncogenic transcriptional signaling, by facilitating permissive chromatin environment

10.2217/nnm.12.80 239 SunX.HuangX.LiuL.ShenW.ZhengF.LiuM.et al (2024)

The no-observed-adverse-effect-level from 60-day studies was determined to be 5,000 mg/kg body weight/day [35]

[PubMed] [Wiley] Ha SB, Smith AP, Howden R, Dietrich WM, Bugg S, OConnell MJ, Goldsbrough PB, Cobbett CS

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