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A study published in PMC examining chemical intolerance and mast cell activation found that alterations in the redox system, glutathione depletion, and pro-inflammatory cytokines interact to affect mast cell behavior. 13 When glutathione is depleted, oxidative stress increases, which can trigger mast cell activation through multiple pathways
PubMed record Dadzie OE, et al
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Fecal microbiota transplantation derived from humans with obesity to GF mice caused excessive weight gain compared to lean ones (110)
Their mechanisms are plausible because they can influence growth hormone and insulin-like growth factor-1 signalling