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Stress and poor sleep are both documented contributors to weight regain and increased appetite

Participants received once-weekly subcutaneous injections of retatrutide at varying doses or placebo over 24 weeks, with a structured dose-escalation period built into the protocol to improve tolerability

Kidney failure or end-stage renal disease can result from damage to this sensitive filtering mechanism caused by diabetes

Published August 4, 2023

Companion Supplies & Routine Support Retatrutide + MOTS-c Dosage Chart This Retatrutide + MOTS-c dosage chart summarizes the retatrutide weekly titration and MOTS-c pulse dosing patterns shown in the dosing section above

J Investig Med