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If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable

Toxicological Information Patch test in humans (50%): well tolerated RIPT (50%): non-sensitizing HET CAM (50%): slight irritant Systemic Tests Neutral red test: slight cytotoxicity AMES test: non-mutagenic 11

They can support mechanistic hypotheses about endothelial response and microvascular repair, but they do not establish human wound healing efficacy, cardiovascular benefit, clinical safety, or suitability for any condition where abnormal angiogenesis could be biologically relevant

For localized goals

The small sample size is also listed as another potential limitation of the study

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