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doi: 10.1002/iub.2046 129 VinuNavarroJHerrero-CerveraAGarca-CubasMAndrs-BlascoIMartnez-HervsSet al

Novel GLP-1-based Medications for Type 2 Diabetes and Obesity

By now, it has been established that the primary function of GLP-1 and GLP-1RA is to modulate brain regions that regulate appetite by influencing the release of neurotransmitters and peptides involved in hunger and energy balance

Dapagliflozin reduced the primary composite outcome (sustained 50% eGFR decline, ESKD, or death from renal or cardiovascular causes) by 39% compared to placebo [47]

Theres no strong evidence that timing makes a meaningful difference in how GLP-1 probiotics affect appetite or weight

By proving that semaglutide acts directly on the liver's internal architecture, we open the door for more precise treatments for the millions living with MASH and advanced fibrosis