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We next asked whether PDS5B affects RAD51-mediated DNA strand exchange

* This process effectively upregulates the body's natural resolution of inflammation

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The pivotal trial supporting its 2010 FDA approval enrolled 816 HIV-infected adults with clinically defined lipodystrophy, and Phase 3 data documented visceral fat reductions of roughly 15-18% over 26 weeks of treatment a result robust enough to clear FDA review for a defined medical indication