Additionally, these medications are often dosed weekly, rather than daily
Therefore, during DUL treatment, we should pay close attention to the related signs of pancreatitis, and if pancreatitis occurs, we need to stop the drug immediately (113)
Zepbound activates GLP-1 and GIP receptors simultaneously-reducing appetite significantly within days, slowing gastric emptying by approximately 40%, and producing average weight loss of up to 21% by week 72
A 2025 radiographic study found an average 7% reduction in midfacial volume for every 10 kilograms of total weight lost, with most of the change occurring in superficial facial fat pads
This unique synergistic effect is why it is currently the subject of such intense study regarding metabolic efficiency and lipolysis (fat breakdown)
In pancreatic function, it serves as a crucial incretin hormone, increasing insulin production in response to oral glucose consumption as opposed to intravenous delivery