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Research Context GH secretagogue research is studied extensively in the preclinical literature in models of pituitary endocrinology, growth-factor signaling, and somatotrope cell biology

Firstly, researchers observed that GHK-Cu increases MMP-2 levels in the conditioned media of cultured dermal fibroblasts, a process not replicated by GHK alone, suggesting that the presence of copper is posited to be necessary for this activity

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