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Evidence on B12 and sleep is mixed: B12 helps regulate circadian rhythm in some contexts, yet high B12 status has been linked with shorter sleep in others

Research data supporting these mechanisms is widely available in global biomedical databases

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This is usually due to paler skin and water retention caused by the deficiency

4.2 Animals Approximately six-week-old SD rats weighing approximately 220 g were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd