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Evidence on B12 and sleep is mixed: B12 helps regulate circadian rhythm in some contexts, yet high B12 status has been linked with shorter sleep in others

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Research data supporting these mechanisms is widely available in global biomedical databases

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This is usually due to paler skin and water retention caused by the deficiency

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4.2 Animals Approximately six-week-old SD rats weighing approximately 220 g were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd

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