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The development of GLP-1 receptor agonists Native GLP-1 is unsuitable itself as a therapeutic agent because of its short half-life in vivo
The effect of tirzepatide on 24-hour mean systolic BP, diastolic BP, and heart rate (HR) measured during 24-hour ambulatory BP monitoring (ABPM) in individuals living with obesity without T2DM, has been evaluated in the SURMOUNT-1 ABPM sub-study.34 After 36 weeks of treatment, tirzepatide was associated with statistically significant and clinically meaningful reductions in the mean 24-hour systolic BP at all doses and reduced diastolic BP at the 2 lower doses.34 Simultaneously, tirzepatide treatment was associated with a dose-dependent increase in the mean 24-hour HR.34 Fortunately, there is no clear evidence that tirzepatide increases the risk of atrial fibrillation.35 5
We believe these food groups should be studied, given the risk factors of obesity, diabetes, and chronic inflammation underlying diverticular disease
Zhou D, Liu H, Zheng L, et al
However, I know the importance of exercise , especially at my age