Blackburn AC, Woollatt E, Sutherland GR, Board PG
This research was supported by Tianjin Scientific Research Projects in Key Areas of Traditional Chinese Medicine (2025017)
5-Amino-1MQ reduces NNMT, improving fat function, inflammation, mitochondrial output, and muscle repair.[23][32] In adipocytes, it boosts NAD+ by preventing its wasteful methylation, leading to better glucose handling
Alpha-synuclein aggregation in Parkinsons disease
In the United States alone, unpaid caregiving costs were estimated at $271 billion in 2021, underscoring the urgency of developing cost-effective treatments that not only alleviate symptoms but also slow disease progression (AlzheimersAssociation, 2022)
We further examine the molecular engineering of photosensitizers to improve their pharmacodynamic and pharmacokinetic properties, increase their molecular specificity and allow image guidance of PDT, and investigate engineered cellular models for the design and optimization of PDT and PDP