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Renal reabsorption is efficient at low plasma concentrations but becomes saturated at higher levels, leading to increased clearance

In Russia, epithalon is clinically used to treat hormone-dependent tumors, as well as menopause-related symptoms and anovulatory infertility [8]

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The first group consisted of healthy, untreated sentinel rats, which were included to provide echocardiographic and biochemical reference values at the end of the study

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If symptoms return, a second injection can be used after at least 1 hour