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CRP binds and aggregates oxidized low-density lipoprotein (ox-LDL) and enhances macrophage oxLDL uptake, promoting mitogen-activated protein kinase activation (171) required for foam cell formation (172)

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Synthesized for laboratory research, GHK-Cu has been widely studied for its involvement in extracellular matrix regulation, collagen signaling, and gene expression related to tissue maintenance and repair

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doi: 10.1007/s00018-005-5163-7