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Author Contributions Jos Luis Grriz provided expert clinical opinion and critical revision of the manuscript for important intellectual content and has helped establish the structure and contents of the manuscript

FDA approval proves that a specific formulation, at a specific dose, for a specific indication, met the endpoints in controlled clinical trials

Internally, fibroblast activity, collagen synthesis signaling, and anti-inflammatory gene modulation are underway

This dual mechanism may enhance outcomes for GERD specifically compared to purely systemic delivery

I lost weight quickly on a GLP1 will the defense blame weight loss instead of the drug