Together, these observations lead to the conclusion that the formation of NAPQI by Cyp2E1 and the formation of protein adducts, especially on mitochondria, are initiating events leading to mitochondrial dysfunction and mitochondrial oxidant stress (Fig
Bhat AH, Dar KB, Anees S, Zargar MA, Masood A, Sofi MA, Ganie SA (2015) Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases
High oral bioavailability Caco-2 cell assays showed excellent passive and active membrane transport with no detectable efflux (Neelakantan et al., 2018)
From the perspective of mitochondrial iron metabolism, iron-export transporters such as ferroportin 1 (FPN1) and ATP-binding cassette subfamily B member 8 (ABCB8) are crucial for maintaining mFe homeostasis
gamma-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor
Investigao do mecanismo de ao preventivo da Spirulina platensis nas alteraes do acoplamento eletromecnico induzidas pelo treinamento de fora em tero de ratas Wistar [dissertao]