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doi: 10.1111/j.1365-2796.2011.02488.x 271 JammoulMNaddourJMadiAReslanMAHatoumFZeineddineJet al

Significant improvements in the severity and frequency of specific depression-related symptoms only occurred after four weeks of treatment, suggesting that a longer treatment period might be needed to uncover the antidepressant effects of curcumin (100, 101)