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Signs of Vitamin B12 Deficiency Vitamin B12 deficiency can lead to several uncomfortable symptoms, including: Constant fatigue and low energy Difficulty concentrating (brain fog) Mood swings or irritability Weakness and dizziness Tingling sensation or numbness in hands and feet If you notice these symptoms, a simple blood test can determine if youre deficient in Vitamin B12

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USA 113 , 22762281 (2016)

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Biosci Biotechnol Biochem 62, 532534 (1998)

The main cerebral target for THC is type-1 cannabinoid receptors (CB1R), which are widely expressed in the brain and regulate various functions including neurotransmitter release, neuro-astroglial communication, and cellular bioenergetic processes [29,30,31,32]