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This article reviews the potential use of L-carnitine and its derivatives in age-related ocular pathologies, such as AMD, cataract, glaucoma and dry eye syndrome.

This study was funded by Eli Lilly, the maker of Mounjaro

In the context of OA, the inflammatory response triggered by cellular pyroptosis exacerbates cartilage degeneration and synovial inflammation, thereby accelerating OA progression (169)

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Together with accompanying T-lymphocytes, these changes represent the fatty streak, an early histopathological change indicating atherosclerosis