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Partial financial support from Tata Innovation Fellowship (No

International Journal of Molecular Sciences (2018) 2

Clinical data shows tirzepatide produces approximately 35% greater weight loss than semaglutide at comparable treatment durations, achieved through superior receptor coverage rather than medication multiplication

40 In addition, 0.05% dietary (equivalent to 50 mg/kg body weight) cinchonine prevents high-fat-diet-induced obesity of C57BL/6N mice

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These medications are a long-term treatment for obesity management, they are not a temporary solution