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402 However, long-term administration of rapamycin has significant side effects (including skin and metabolic disorders) and inhibits mTORC2

In combination with a GLP-1 some patients benefit from adding phentermine alongside Wegovy or Zepbound when additional appetite suppression is needed, particularly during the early dose-escalation phase of GLP-1 treatment

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The key is to have that larger goal in mind

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