The scientific community now focuses on ferroptosis because of its capacity to break through resistance to standard treatment modalities
Both are studied in tissue repair contexts but via distinct mechanisms
We offer glutathione as an add-in or as part of our Myers' Cocktail package
This remarkable selectivity stems from 5-amino-1MQs specific interaction with the nicotinamide-binding pocket of NNMT, rather than the SAM-binding site common to many methyltransferases
Acknowledgements We thank Drs Henderson and Fowler for assistance with a cryostat used for sectioning tumors, Janet Derten for assisting with the MetaMorph software, Charlie Linch for assisting with analytical flow cytometry, and Tito Woodburn, Heather Hall and Heather Davidson for assisting with cell culture, STRs and mycoplasma testing
Conclusion : TubA provides protection in liver IRI and in an APAP model of liver injury, which have broad clinical implications