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DNA damage: Accumulating mutations that impair gene expression

Additionally, SUMOylation of transcription factors impairs their nuclear localization, further disrupting hormonal signaling cascades (62, 63)

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While they are frequently stacked together, they operate through distinct molecular pathways

In their subsequent research, the increased level of IL-6 due to the peptide vaccine suggested that IL-6 could serve as a good indicator in patients who received the peptide vaccine [135]