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Paavilainen E, et al

[22] The PI3K pathway is activated in two ways: PI3K can be either downstream of RAS, or it can be recruited directly through the multifunctional docking site

Beydoun MA, Gamaldo AA, Canas JA, et al

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This overlap creates potential challenges in distinguishing medication side effects from disease flares, which could delay appropriate escalation of IBD therapy

However, this is rarely what a patient pays at the pharmacy counter