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This includes a personal or family history of medullary thyroid carcinoma (a type of thyroid cancer) or Multiple Endocrine Neoplasia syndrome type 2

Federal Drug Administration have received reports of adverse events, some including hospitalizations on compounded GLP-1 drugs due to dosing errors or incorrect doses with self-administration

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Caution: Details GLP-1R/GIPR/GCGR signaling and metabolic regulation Peptide hormones acting through the glucagon-like peptide-1 receptor ( GLP-1R ), the glucose-dependent insulinotropic polypeptide receptor ( GIPR ), and the glucagon receptor ( GCGR ) play complementary roles in the regulation of glucose metabolism and energy balance [1]