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In some embodiments, the otic formulation or composition comprises about 0.2% by weight of the poloxamer

Solution: Proceed with caution and seek professional oversight

However, we found that it is virtually fully oxidized, when expressed in the periplasm, suggesting that its engineered cysteine residues are completely oxidized by the oxidative folding machinery

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Short-term storage: 2-8C acceptable

Yu, S., Qian, H., Zhang, D