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In fact, ROS-modulating therapies share certain similarities with existing treatments such as chemotherapy and immunotherapy, that is, pro-oxidative stress strategies to further kill tumor cells and other cells, which has been recognized as a promising approach to improve treatment outcomes for decades [564, 565]

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Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed sulfation factor, which later became known as somatomedin

Rapid injection can cause discomfort and may affect peptide distribution

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