Despite the promise of the biologic and kinase-inhibitor approaches, which are currently represented in clinical trials, both have limitations arising from toxicity or specificity considerations and/or cost
GLP-1 influences food and drug reward[J]
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This method is often well-tolerated and provides targeted benefits
Should GLP-1 patches complete clinical development and receive regulatory approval in future, they would undergo health technology assessment by NICE to determine cost-effectiveness and appropriate positioning within NHS treatment pathways
"A typical loading protocol consists of consuming high doses, like 20-25 grams per day, split between 4-5 daily doses, for 5-7 days