Hackford pitched the idea to Jeffrey Katzenberg, who showed interest, the project would end up being distributed through Hollywood Pictures and Buena Vista Pictures, both subsidiaries of The Walt Disney Studios
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PMID: 33415011
Similar strategies may also be used to deplete IgA, as explored with the pre-clinical candidate BHV-1400 [434], which leverages ASGPR biology in a manner similar to BHV-1300 and could represent an alternative to the likely mechanism-of-action of ARGX-121, and to deplete IgE, as shown with lysosomal targeting chimeras coupling pH-sensitive target binding and ASGPR-mediated endolysosomal delivery to FcRn-mediated cellular transport of the potential therapeutic molecule [435]
Jaaro-Peled H, Ayhan Y, Pletnikov MV, Sawa A
Also, there is a need to establish collaborative platforms between interdisciplinary teams, including basic researchers, clinicians, and industry partners, to take bench work to a product or treatment