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GLP-1 receptor agonists (semaglutide, tirzepatide, liraglutide) have shown benefits beyond weight loss in early research: reduced cravings in substance use disorders, potential mood stabilization, decreased inflammation affecting brain health

In a randomized, placebo-controlled trial published in the Journal of Clinical Endocrinology & Metabolism , healthy adults aged 5571 receiving once-nightly subcutaneous GHRH(129) at 10 g/kg for 16 weeks demonstrated a 107% increase in 12-hour integrated growth hormone secretion in men and a 70% increase in women, accompanied by significant elevations in serum insulin-like growth factor 1 (IGF-1) [2]

PMCID: PMC5405115

People fail to recognize these are two completely different classes of peptides working through entirely different biological pathways, and that using them together is superior to using either one alone

This is determined by the presence of a molecule called the intrinsic factor that is essential for the absorption of B12 into your system

Accessed July 4, 2012