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But, genes alone are not enough to trigger it

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CNS Neurol Disord Drug Targets 16:527533 Brigida AL, Schultz S, Cascone M, Antonucci N, Siniscalco D (2017) Endocannabinod signal dysregulation in autism spectrum disorders: a correlation link between inflammatory state and neuro-immune alterations

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We found that in hepatoma HepG2 cells, cystine (oxidized form of cysteine) activated mTORC1 and suppressed the ISR