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NF-B activated microglia, innate immune cells in the central nervous system, can accelerate the tau seeding and propagation of tau pathology, and inactivation of this transcription factor can lead to a slow down of this propagation demonstrated in the mice model (Wang et al., 2022)

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The retrograde pathway traffics S protein to the virion assembly site Finally, to determine whether the anterograde or retrograde pathway is the primary conduit for S protein during SARS-CoV-2 assembly, we utilized a Lys1269Ala/His1271Ala double mutant of S dibasic motif, which is unable to interact with coatomer 10,11

Safety considerations for autoimmune patients on tirzepatide Taking tirzepatide when you have an autoimmune condition introduces specific safety considerations that healthy individuals do not face

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