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placebo in the REWIND trial over a long median follow-up period of 5.4 years (HR for MACE of 0.88

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It also carries real safety concerns and is not an approved product

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As their use has expanded dramatically in recent years, questions about long-term safety, including potential cancer risk, have become increasingly important for both patients and clinicians

The oral versions, the Ozempic pill and the Wegovy pill, should be taken once a day , in the morning on an empty stomach with 4 ounces (or less) of plain water