Store in a cool, dry location away from direct sunlight
This may be related to the fact that AGEs can age and oxygenize the collagen and modify the collagen surface, which is known to affect cell-matrix interactions in a manner leading to exacerbated inflammation and may inhibit tendon repair [45, 46]
And then move to maintain this once every 3-4 weeks
The 5 mg/mL sweet spot keeps all doses within a 0.2-3 mL range that is both practical and measurable
Preclinical studies also describe effects on collagen organization and tendon/ligament healing, as well as protective effects in gastrointestinal injury models
This article is part of the Topical Collection on Pathogenesis of Type 2 Diabetes and Insulin Resistance Rights and permissions About this article Cite this article Hsiao, WY., Guertin, D.A