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In PBMCs, including monocytes, a reduction in zinc concentration, either through the use of the chelator TPEN or by removing zinc from the culture medium, leads to a significant increase in oxidative burst and phagocytosis following infection with gram-positive S
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However, mechanism does not automatically determine timing
Zuo X, Xu W, Xu M, Tian R, Moussalli MJ, Mao F, Zheng X, Wang J, Morris JS, Gagea M, Eng C, Kopetz S , Maru DM, Rashid A, Broaddus R, Wei D, Hung MC, Sood AK, Shureiqi I
e BioMedicine 74 , 103739 (2021)
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