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Role of hepatocellular regeneration and hepatolobular healing in the final outcome of liver injury

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The senior author of the paper is HDRF Depression Task Force member Dr

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TREM2 agonists, such as AL002, promote microglial transformation toward the anti-inflammatory M2 phenotype, thereby reducing the release of pro-inflammatory M1 cytokines (e.g., TNF-, IL-1) and indirectly mitigating inflammation-driven ferroptotic cascades