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The GSH-GSSG pair acts as the redox buffer within the glutathione system, preserving optimal redox balance in subcellular structures to the entire organism [4]

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AMPK is also a potential target for therapeutic intervention and preventive strategies in other cardiometabolic diseases (130)

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The share who report ever taking these drugs rises to about four in ten (43%) among adults who have been told by a doctor that they have diabetes, a quarter (26%) of adults who have been told they have heart disease, and one in five (22%) adults who have been told by a doctor that they are overweight or obese in the past five years (some of whom also have diabetes or heart disease)

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