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If approved, your medication is dispensed by a U.S.-licensed pharmacy and shipped discreetly to your door each month with ongoing provider oversight

This is important because GLP-1 drugs were originally designed to have a long half-life in blood to maximise their efficacy in the treatment of diabetes which prevents them from entering the brain (Hlscher)

These effects explain both their potential benefits and many of their common gastrointestinal side effects

On top of these administrative hurdles, drug shortages have plagued the market, making it difficult for patients to start or continue treatment

If nausea severely limits your ability to eat, speak with your PlexusDx clinician about anti-nausea medication like ondansetron (Zofran) or granisetron, which are safe to use alongside tirzepatide and provide relief while your body adapts