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Specifically, nuclear translocation of NFB was significantly inhibited at 50 M of ginsenoside Rh1 pretreatment [218]

Since the latter study had a placebo group which had redox and methylation biomarkers measured at the beginning and end of the intervention, we use this placebo group as a control group for all three studies in order to determine if the changes in redox and methylation metabolism were significant as a result of the three interventions

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In the long-term toxicity experiment, continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose, providing a safety basis for its further research and application

Insulin has remained the cornerstone of treatment in type 1 diabetes since its discovery by Banting and Best in 1922 [2]