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Identification of biological functions of distinct ferroptosis subtypes To clarify the functional differences in different ferroptosis subtypes, we performed GSVA analysis and found that metabolism-related signaling pathway, oxidative phosphorylation, and the TCA cycle were significantly upregulated in Subtype 1, while DNA regulation, chemokine signaling, cytokine receptor interaction, autoimmune diseases, various immune cells pathways such as T cell receptor, B cell receptor, Nod-like receptor, natural killer cells activation, and Toll-like receptor pathway were upregulated in subtype 2(Fig
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Consistently, the T3 effect on the percentage of TMCA was abolished in the ileum of LTRKO mice (Fig
Nutr Hosp 26(3):650654 Baewicz A, Klatka M, Astel A, Partyka M, Kocjan R (2013) Differences in trace metal concentrations (Co, Cu, Fe, Mn, Zn, Cd, and Ni) in whole blood, plasma, and urine of obese and nonobese children